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Do β-Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration?

It is widely accepted that the brain responds to mechanical trauma and development of most neurodegenerative diseases with an inflammatory sequelae that was once thought exclusive to systemic immunity. Mostly cationic peptides, such as the β-defensins, originally assigned an antimicrobial function a...

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Detalhes bibliográficos
Main Authors: Wesley M. Williams, Rudy J. Castellani, Aaron Weinberg, George Perry, Mark A. Smith
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2012-01-01
Colecção:The Scientific World Journal
Acesso em linha:http://dx.doi.org/10.1100/2012/905785
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