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Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood. Here, we show that DNA methylation is enr...

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書目詳細資料
Main Authors: Maunakea, Alika K, Chepelev, Iouri, Cui, Kairong, Zhao, Keji
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817542/
https://ncbi.nlm.nih.gov/pubmed/23938295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.110
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