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Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood. Here, we show that DNA methylation is enr...

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Detalhes bibliográficos
Main Authors: Maunakea, Alika K, Chepelev, Iouri, Cui, Kairong, Zhao, Keji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817542/
https://ncbi.nlm.nih.gov/pubmed/23938295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.110
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