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Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood. Here, we show that DNA methylation is enr...

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Bibliografische gegevens
Hoofdauteurs: Maunakea, Alika K, Chepelev, Iouri, Cui, Kairong, Zhao, Keji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817542/
https://ncbi.nlm.nih.gov/pubmed/23938295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.110
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