Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood. Here, we show that DNA methylation is enr...

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Hauptverfasser: Maunakea, Alika K, Chepelev, Iouri, Cui, Kairong, Zhao, Keji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817542/
https://ncbi.nlm.nih.gov/pubmed/23938295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.110
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