The Scavenger Protein Apoptosis Inhibitor of Macrophages (AIM) Potentiates the Antimicrobial Response against Mycobacterium tuberculosis by Enhancing Autophagy

Apoptosis inhibitor of macrophages (AIM), a scavenger protein secreted by tissue macrophages, is transcriptionally regulated by the nuclear receptor Liver X Receptor (LXR) and Retinoid X Receptor (RXR) heterodimer. Given that LXR exerts a protective immune response against M. tuberculosis, here we a...

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Autori principali: Sanjurjo, Lucía, Amézaga, Núria, Vilaplana, Cristina, Cáceres, Neus, Marzo, Elena, Valeri, Marta, Cardona, Pere-Joan, Sarrias, Maria-Rosa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817138/
https://ncbi.nlm.nih.gov/pubmed/24223991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079670
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