Low Dose Aerosol Fitness at the Innate Phase of Murine Infection Better Predicts Virulence amongst Clinical Strains of Mycobacterium tuberculosis

BACKGROUND: Evaluation of a quick and easy model to determine the intrinsic ability of clinical strains to generate active TB has been set by assuming that this is linked to the fitness of Mycobacterium tuberculosis strain at the innate phase of the infection. Thus, the higher the bacillary load, th...

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Main Authors: Caceres, Neus, Llopis, Isaac, Marzo, Elena, Prats, Clara, Vilaplana, Cristina, de Viedma, Dario Garcia, Samper, Sofía, Lopez, Daniel, Cardona, Pere-Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250398/
https://ncbi.nlm.nih.gov/pubmed/22235258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029010
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