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Prophylactic Effect of a Therapeutic Vaccine against TB Based on Fragments of Mycobacterium tuberculosis

The prophylactic capacity of the RUTI® vaccine, based on fragmented cells of Mycobacterium tuberculosis, has been evaluated in respect to aerosol challenge with virulent bacilli. Subcutaneous vaccination significantly reduced viable bacterial counts in both lungs and spleens of C57Bl mice, when chal...

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Detalhes bibliográficos
Main Authors: Vilaplana, Cristina, Gil, Olga, Cáceres, Neus, Pinto, Sergio, Díaz, Jorge, Cardona, Pere-Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101251/
https://ncbi.nlm.nih.gov/pubmed/21647222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020404
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