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Prophylactic Effect of a Therapeutic Vaccine against TB Based on Fragments of Mycobacterium tuberculosis

The prophylactic capacity of the RUTI® vaccine, based on fragmented cells of Mycobacterium tuberculosis, has been evaluated in respect to aerosol challenge with virulent bacilli. Subcutaneous vaccination significantly reduced viable bacterial counts in both lungs and spleens of C57Bl mice, when chal...

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Библиографические подробности
Главные авторы: Vilaplana, Cristina, Gil, Olga, Cáceres, Neus, Pinto, Sergio, Díaz, Jorge, Cardona, Pere-Joan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101251/
https://ncbi.nlm.nih.gov/pubmed/21647222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020404
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