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Prophylactic Effect of a Therapeutic Vaccine against TB Based on Fragments of Mycobacterium tuberculosis

The prophylactic capacity of the RUTI® vaccine, based on fragmented cells of Mycobacterium tuberculosis, has been evaluated in respect to aerosol challenge with virulent bacilli. Subcutaneous vaccination significantly reduced viable bacterial counts in both lungs and spleens of C57Bl mice, when chal...

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Dettagli Bibliografici
Autori principali: Vilaplana, Cristina, Gil, Olga, Cáceres, Neus, Pinto, Sergio, Díaz, Jorge, Cardona, Pere-Joan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101251/
https://ncbi.nlm.nih.gov/pubmed/21647222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020404
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