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TET1 Controls CNS 5-methylcytosine Hydroxylation, Active DNA Demethylation, Gene Transcription and Memory Formation
Dynamic changes in 5-methylcytosine (5mC) have been implicated in the regulation of gene expression critical for consolidation of memory. However, little is known about how these changes in 5mC are regulated in the adult brain. The enzyme Tet methylcytosine dioxygenase 1 (TET1) has been shown to pro...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816951/ https://ncbi.nlm.nih.gov/pubmed/24050399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.08.032 |
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