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Inhibiting the intrinsic pathway of coagulation with a FXII-targeting RNA Aptamer
BACKGROUND: Exposure of the plasma protein factor XII to an anionic surface generates activated factor XII that not only triggers the intrinsic pathway of blood coagulation through the activatio of factor XI, but also mediates various vascular responses through activation of the plasma contact syste...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816843/ https://ncbi.nlm.nih.gov/pubmed/23692437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12302 |
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