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Thiopurine methyltransferase genotyping in Palestinian childhood acute lymphoblastic leukemia patients
BACKGROUND: The genetic polymorphism of thiopurine methyltransferase (TPMT) is well characterized in most populations. Four common polymorphic alleles are associated with impaired activity of the enzyme. These are TPMT*2 (238G>C), TPMT*3B (c.460G>A), TPMT*3A (c.460G>A and c.719A>G) and T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816621/ https://ncbi.nlm.nih.gov/pubmed/24499706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2052-1839-13-3 |
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