Genetic Polymorphism of Thiopurine S-methyltransferase in Children with Acute Lymphoblastic Leukemia in Jordan

BACKGROUND AND AIMS: It has been demonstrated that homozygote and heterozygote mutant allele carriers for thiopurine S-methyltransferase (TPMT) are at high risk of developing myelosuppression after receiving standard doses of 6-mercaptopurine (6-MP). The aim of this study was to determine the freque...

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Опубликовано в: :Asian Pac J Cancer Prev
Главные авторы: Alsous, Mervat, Yousef, Al-Motassem, Jalil, Mariam Abdel, Zawiah, Mohammed, Yacoub, Shorouq, Momani, Deema, Gharabli, Alia, Omar, Suha, Rihani, Rawad
Формат: Artigo
Язык:Inglês
Опубликовано: West Asia Organization for Cancer Prevention 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844618/
https://ncbi.nlm.nih.gov/pubmed/29373914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2018.19.1.199
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