Molecular Basis of 9G4 B Cell Autoreactivity in Human Systemic Lupus Erythematosus

9G4(+) IgG Abs expand in systemic lupus erythematosus (SLE) in a disease-specific fashion and react with different lupus Ags including B cell Ags and apoptotic cells. Their shared use of VH4-34 represents a unique system to understand the molecular basis of lupus autoreactivity. In this study, a lar...

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Detalhes bibliográficos
Main Authors: Richardson, Christopher, Chida, Asiya Seema, Adlowitz, Diana, Silver, Lin, Fox, Erin, Jenks, Scott A., Palmer, Elise, Wang, Youliang, Heimburg-Molinaro, Jamie, Li, Quan-Zhen, Mohan, Chandra, Cummings, Richard, Tipton, Christopher, Sanz, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816606/
https://ncbi.nlm.nih.gov/pubmed/24108696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202263
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