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In vitro study of combined cilengitide and radiation treatment in breast cancer cell lines
BACKGROUND: Brain metastasis from breast cancer poses a major clinical challenge. Integrins play a role in regulating adhesion, growth, motility, and survival, and have been shown to be critical for metastatic growth in the brain in preclinical models. Cilengitide, an αvβ3/αvβ5 integrin inhibitor, h...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816586/ https://ncbi.nlm.nih.gov/pubmed/24153102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-8-246 |
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