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Lineage Extrinsic and Intrinsic Control of Immunoregulatory Cell Numbers by SHIP

We previously showed that germline or induced SHIP-deficiency expands immunoregulatory cell numbers in T lymphoid and myeloid lineages. We postulated these increases could be interrelated. Here we show that myeloid specific ablation of SHIP leads to expansion of both myeloid-derived suppressor cell...

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Detalhes bibliográficos
Main Authors: Collazo, Michelle M, Paraiso, Kim HT, Park, Mi-Young, Hazen, Amy L, Kerr, William G
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816569/
https://ncbi.nlm.nih.gov/pubmed/22535653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142092
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