Epigenetic drug 5-azacytidine impairs proliferation of rat limb buds in an organotypic model-system in vitro

AIM: To establish an organotypic in vitro model of limb bud development to verify whether epigenetic drug and teratogen 5-azacytidine (5azaC) has an effect on limb buds independent of its effects on the placenta. METHODS: Fischer strain rat fore- and hindlimb buds were microsurgically isolated from...

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Bibliografiske detaljer
Main Authors: Mužić, Vedrana, Katušić Bojanac, Ana, Jurić-Lekić, Gordana, Himelreich, Marta, Tupek, Katarina, Šerman, Ljiljana, Marn, Nina, Sinčić, Nino, Vlahović, Maja, Bulić-Jakuš, Floriana
Format: Artigo
Sprog:Inglês
Udgivet: Croatian Medical Schools 2013
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816559/
https://ncbi.nlm.nih.gov/pubmed/24170728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2013.54.489
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