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Epigenetic drug 5-azacytidine impairs proliferation of rat limb buds in an organotypic model-system in vitro
AIM: To establish an organotypic in vitro model of limb bud development to verify whether epigenetic drug and teratogen 5-azacytidine (5azaC) has an effect on limb buds independent of its effects on the placenta. METHODS: Fischer strain rat fore- and hindlimb buds were microsurgically isolated from...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Croatian Medical Schools
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816559/ https://ncbi.nlm.nih.gov/pubmed/24170728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2013.54.489 |
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