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Epigenetically inactivated RASSF1A as a tumor biomarker

RASSF1A, one of the eight isoforms of the RASSF1 gene, is a tumor suppressor gene that influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated by mutations, loss of heterozygosity, and, most commonly, by promoter hypermethylation. Epigenetic inactivation of RASSF1A...

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Detalhes bibliográficos
Publicado no:Bosn J Basic Med Sci
Main Authors: Raos, Dora, Ulamec, Monika, Bojanac, Ana Katusic, Bulic-Jakus, Floriana, Jezek, Davor, Sincic, Nino
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292865/
https://ncbi.nlm.nih.gov/pubmed/33175673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17305/bjbms.2020.5219
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