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Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells

Antibodies that modulate receptor function have great untapped potential in the control of stem cell differentiation. In contrast to many natural ligands, antibodies are stable, exquisitely specific, and are unaffected by the regulatory mechanisms that act on natural ligands. Here we describe an inn...

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Detalhes bibliográficos
Main Authors: Melidoni, Anna N., Dyson, Michael R., Wormald, Sam, McCafferty, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816485/
https://ncbi.nlm.nih.gov/pubmed/24082130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312062110
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