An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives

We have developed a universally applicable system for conditional gene expression in embryonic stem (ES) cells that relies on tamoxifen-dependent Cre recombinase-loxP site-mediated recombination and bicistronic gene-trap expression vectors that allow transgene expression from endogenous cellular pro...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Vallier, Ludovic, Mancip, Jimmy, Markossian, Suzy, Lukaszewicz, Agnès, Dehay, Colette, Metzger, Daniel, Chambon, Pierre, Samarut, Jacques, Savatier, Pierre
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041617198
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