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Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation

Tissue factor (TF) pathway inhibitor (TFPI) is a well-characterized activated factor X (FXa)-dependent inhibitor of TF-initiated coagulation produced in two alternatively spliced isoforms, TFPIα and TFPIβ. The TFPIα C terminus has a basic sequence nearly identical to a portion of the factor V (FV) B...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wood, Jeremy P., Bunce, Matthew W., Maroney, Susan A., Tracy, Paula B., Camire, Rodney M., Mast, Alan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816478/
https://ncbi.nlm.nih.gov/pubmed/24127605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310444110
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