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Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction

Intraocular inflammatory diseases are a common cause of severe visual impairment and blindness. In an acute mouse model of autoimmune retinal disease, we demonstrate that treatment with the HMG-CoA reductase inhibitor, lovastatin, suppresses clinical ocular pathology, retinal vascular leakage and le...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harry, Rachel, Gegg, Matthew, Hankey, Deborah, Zambarakji, Hadi, Pryce, Gareth, Baker, David, Calder, Virginia, Adamson, Peter, Greenwood, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816391/
https://ncbi.nlm.nih.gov/pubmed/15699169
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