Identification of Tamoxifen-Induced Coregulator Interaction Surfaces within the Ligand-Binding Domain of Estrogen Receptors

Tamoxifen is a selective estrogen receptor (ER) modulator that is clinically used as an antagonist to treat estrogen-dependent breast cancers but displays unwanted agonistic effects in other tissues. Previous studies on ERα have delineated a role of the N-terminal activation function AF-1 in mediati...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Heldring, Nina, Nilsson, Maria, Buehrer, Benjamin, Treuter, Eckardt, Gustafsson, Jan-Åke
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2004
Matèries:	Transcriptional Regulation
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15060164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.8.3445-3459.2004
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