Probing the heterologous metabolism supporting 6‐deoxyerythronolide B biosynthesis in Escherichia coli

Heterologous biosynthesis offers a new way to capture the medicinal properties presented by complex natural products. In this study, production of 6‐deoxyerythronolide B (6dEB), the polyketide precursor to the antibiotic erythromycin, was used to probe the heterologous pathways needed for Escherichi...

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Bibliografiske detaljer
Main Authors: Zhang, Haoran, Wang, Yong, Boghigian, Brett, Pfeifer, Blaine A.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815759/
https://ncbi.nlm.nih.gov/pubmed/21261933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2009.00099.x
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