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Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions
Polyketides represent a significant fraction of all natural products. Many possess pharmacological activity which makes them attractive drug candidates. The production of the parent macrocyclic aglycones are catalyzed by multimodular polyketide synthases utilizing short-chain acyl-CoA monomers. When...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076518/ https://ncbi.nlm.nih.gov/pubmed/21337322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.23069 |
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