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Positional Cloning of the Mouse Circadian Clock Gene

We used positional cloning to identify the circadian Clock gene in mice. Clock is a large transcription unit with 24 exons spanning ~100,000 bp of DNA from which transcript classes of 7.5 and ~10 kb arise. Clock encodes a novel member of the bHLH–PAS family of transcription factors. In the Clock mut...

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Hlavní autoři: King, David P., Zhao, Yaliang, Sangoram, Ashvin M., Wilsbacher, Lisa D., Tanaka, Minoru, Antoch, Marina P., Steeves, Thomas D. L., Vitaterna, Martha Hotz, Kornhauser, Jon M., Lowrey, Phillip L., Turek, Fred W., Takahashi, Joseph S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815553/
https://ncbi.nlm.nih.gov/pubmed/9160755
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