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A Practical Method for the Synthesis of Highly Enantioenriched trans-1,2-Amino Alcohols

[Image: see text] A highly enantioselective addition of phenyl carbamate to meso-epoxides has been developed to efficiently generate protected trans-1,2-amino alcohols. This transformation is promoted by an oligomeric (salen)Co–OTf catalyst and has been used to prepare two useful 2-aminocycloalkanol...

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Detalles Bibliográficos
Main Authors: Birrell, James A., Jacobsen, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815482/
https://ncbi.nlm.nih.gov/pubmed/23742206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401013s
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