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Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis

[Image: see text] Chiral pentose sugars mediate the enantioselective synthesis of amino acid precursors, with the magnitude of the chiral induction dictated by a subtle cooperativity between sugar hydroxyl groups. Ribose and lyxose give opposite chiral preferences, and theoretical calculations revea...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Wagner, Alexander J., Zubarev, Dmitry Yu., Aspuru-Guzik, Alán, Blackmond, Donna G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408343/
https://ncbi.nlm.nih.gov/pubmed/28470050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00085
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