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One-Pot Multicomponent Coupling Methods for the Synthesis of Diastereo- and Enantioenriched (Z)-Trisubstituted Allylic Alcohols

(Z)-Trisubstituted allylic alcohols are widespread structural motifs in natural products and biologically active compounds but are difficult to directly prepare. Introduced herein is a general one-pot multicomponent coupling method for the synthesis of (Z)-α,α,β-trisubstituted allylic alcohols. (Z)-...

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Detalhes bibliográficos
Main Authors: Kerrigan, Michael H., Jeon, Sang-Jin, Chen, Young K., Salvi, Luca, Carroll, Patrick J., Walsh, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749706/
https://ncbi.nlm.nih.gov/pubmed/19476375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809821x
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