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Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation
Most methods for next-generation sequencing (NGS) data analyses incorporate information regarding allele frequencies using the assumption of Hardy–Weinberg equilibrium (HWE) as a prior. However, many organisms including those that are domesticated, partially selfing, or with asexual life cycles show...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814885/ https://ncbi.nlm.nih.gov/pubmed/23950147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157388.113 |
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