Transforming Growth Factor-β3 (TGF-β3) Knock-in Ameliorates Inflammation Due to TGF-β1 Deficiency While Promoting Glucose Tolerance

Three homologues of TGF-β exist in mammals as follows: TGF-β1, TGF-β2, and TGF-β3. All three proteins share high homology in their amino acid sequence, yet each TGF-β isoform has unique heterologous motifs that are highly conserved during evolution. Although these TGF-β proteins share similar proper...

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Detalhes bibliográficos
Main Authors: Hall, Bradford E., Wankhade, Umesh D., Konkel, Joanne E., Cherukuri, Karthik, Nagineni, Chandrasekharam N., Flanders, Kathleen C., Arany, Praveen R., Chen, Wanjun, Rane, Sushil G., Kulkarni, Ashok B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814801/
https://ncbi.nlm.nih.gov/pubmed/24056369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.480764
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