Conditional overexpression of TGF-β1 disrupts mouse salivary gland development and function

Transforming growth factor-β (TGF-β) signaling is known to affect salivary gland physiology by influencing branching morphogenesis, regulating ECM deposition, and controlling immune homeostasis. To study the role of TGF-β1 in the salivary gland, we created a transgenic mouse (β1(glo)) that condition...

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Main Authors: Hall, Bradford E., Zheng, Changyu, Swaim, William D., Cho, Andrew, Nagineni, Chandrasekharam N., Eckhaus, Michael A., Flanders, Kathleen C., Ambudkar, Indu S., Baum, Bruce J., Kulkarni, Ashok B.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847636/
https://ncbi.nlm.nih.gov/pubmed/20142803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.5
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