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Regulation of the Na(+)/Ca(2+) Exchanger by Pyridine Nucleotide Redox Potential in Ventricular Myocytes

The cardiac Na(+)/Ca(2+) exchanger (NCX) is the major Ca(2+) efflux pathway on the sarcolemma, counterbalancing Ca(2+) influx via L-type Ca(2+) current during excitation-contraction coupling. Altered NCX activity modulates the sarcoplastic reticulum Ca(2+) load and can contribute to abnormal Ca(2+)...

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Autors principals: Liu, Ting, O'Rourke, Brian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814794/
https://ncbi.nlm.nih.gov/pubmed/24045952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496588
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