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Na(+) channel regulation by Ca(2+)/calmodulin and Ca(2+)/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes(†)
AIMS: Calmodulin (CaM) regulates Na(+) channel gating through binding to an IQ-like motif in the C-terminus. Ca(2+)/CaM-dependent protein kinase II (CaMKII) regulates Ca(2+) handling, and chronic overactivity of CaMKII is associated with left ventricular hypertrophy and dysfunction and lethal arrhyt...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802203/ https://ncbi.nlm.nih.gov/pubmed/19797425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp324 |
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