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Role of Sodium-Calcium Exchanger in Modulating the Action Potential of Ventricular Myocytes From Normal and Failing Hearts
Increased Na(+)-Ca(2+) exchange (NCX) activity in heart failure and hypertrophy may compensate for depressed sarcoplasmic reticular Ca(2+) uptake, provide inotropic support through reverse-mode Ca(2+) entry, and/or deplete intracellular Ca(2+) stores. NCX is electrogenic and depends on Na(+) and Ca(...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1237121/ https://ncbi.nlm.nih.gov/pubmed/12805237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000080932.98903.D8 |
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