Sparing of the Dystrophin-Deficient Cranial Sartorius Muscle Is Associated with Classical and Novel Hypertrophy Pathways in GRMD Dogs

Both Duchenne and golden retriever muscular dystrophy (GRMD) are caused by dystrophin deficiency. The Duchenne muscular dystrophy sartorius muscle and orthologous GRMD cranial sartorius (CS) are relatively spared/hypertrophied. We completed hierarchical clustering studies to define molecular mechani...

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Autores principales: Nghiem, Peter P., Hoffman, Eric P., Mittal, Priya, Brown, Kristy J., Schatzberg, Scott J., Ghimbovschi, Svetlana, Wang, Zuyi, Kornegay, Joe N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2013
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814684/
https://ncbi.nlm.nih.gov/pubmed/24160322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.07.013
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