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Sparing of the Dystrophin-Deficient Cranial Sartorius Muscle Is Associated with Classical and Novel Hypertrophy Pathways in GRMD Dogs

Both Duchenne and golden retriever muscular dystrophy (GRMD) are caused by dystrophin deficiency. The Duchenne muscular dystrophy sartorius muscle and orthologous GRMD cranial sartorius (CS) are relatively spared/hypertrophied. We completed hierarchical clustering studies to define molecular mechani...

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Detalhes bibliográficos
Main Authors: Nghiem, Peter P., Hoffman, Eric P., Mittal, Priya, Brown, Kristy J., Schatzberg, Scott J., Ghimbovschi, Svetlana, Wang, Zuyi, Kornegay, Joe N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814684/
https://ncbi.nlm.nih.gov/pubmed/24160322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.07.013
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