Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1

The RNPC1 RNA-binding protein, also called Rbm38, is a target of p53 and a repressor of p53 mRNA translation. Thus, the p53–RNPC1 loop is critical for modulating p53 tumor suppression, but it is not clear how the loop is regulated. Here, we showed that RNPC1 is phosphorylated at Ser195 by glycogen s...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Min, Zhang, Jin, Chen, Xiangling, Cho, Seong-Jun, Chen, Xinbin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2013
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814645/
https://ncbi.nlm.nih.gov/pubmed/24142875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.221739.113
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller