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An age-related numerical and functional deficit in CD19(+)CD24(hi)CD38(hi) B cells is associated with an increase in systemic autoimmunity
Autoimmunity increases with aging indicative of reduced immune tolerance, but the mechanisms involved are poorly defined. In recent years, subsets of B cells with immunoregulatory properties have been identified in murine models of autoimmune disorders, and these cells downregulate immune responses...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Blackwell Publishing Ltd
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814412/ https://ncbi.nlm.nih.gov/pubmed/23755918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12114 |
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