Increased frequency of circulating CD19+CD24(hi)CD38(hi) B cells with regulatory capacity in patients with Ankylosing spondylitis (AS) naïve for biological agents

Our objective was to study the frequency of circulating CD19+CD24(hi)CD38(hi) B cells (Breg) in AS patients. To this end, peripheral blood was drawn from AS patients naïve for TNF blockers (AS/nb) (n = 42) and healthy controls (HC) (n = 42). Six patients donated blood for a second time, 6 months aft...

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Pubblicato in:PLoS One
Autori principali: Bautista-Caro, María-Belén, de Miguel, Eugenio, Peiteado, Diana, Plasencia-Rodríguez, Chamaida, Villalba, Alejandro, Monjo-Henry, Irene, Puig-Kröger, Amaya, Sánchez-Mateos, Paloma, Martín-Mola, Emilio, Miranda-Carús, María-Eugenia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500370/
https://ncbi.nlm.nih.gov/pubmed/28683133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180726
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