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NK cell immunesenescence is increased by psychological but not physical stress in older adults associated with raised cortisol and reduced perforin expression

NK cell cytotoxicity (NKCC) reduces with age and this has been associated previously with increased mortality. The immune response is also modulated by stress, and here, we assessed the effect of the physical stress of hip fracture and the psychological stress of depression on NKCC in an aged immune...

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Detalhes bibliográficos
Publicado no:Age (Dordr)
Main Authors: Duggal, Niharika Arora, Upton, Jane, Phillips, Anna C., Hampson, Peter, Lord, Janet M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320126/
https://ncbi.nlm.nih.gov/pubmed/25663421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9748-2
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