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Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

There is uncertainty about the site(s) of action of the antidiabetic thiazolidinediones (TZDs). These drugs are agonist ligands of the transcription factor PPARγ, which is abundant in adipose tissue but is normally present at very low levels in liver and muscle. We have studied the effects of TZDs i...

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Bibliografische gegevens
Hoofdauteurs: Chao, Lily, Marcus-Samuels, Bernice, Mason, Mark M., Moitra, Jaideep, Vinson, Charles, Arioglu, Elif, Gavrilova, Oksana, Reitman, Marc L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC381440/
https://ncbi.nlm.nih.gov/pubmed/11086023
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