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Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
RlmJ catalyzes the m(6)A2030 methylation of 23S rRNA during ribosome biogenesis in Escherichia coli. Here, we present crystal structures of RlmJ in apo form, in complex with the cofactor S-adenosyl-methionine and in complex with S-adenosyl-homocysteine plus the substrate analogue adenosine monophosp...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814359/ https://ncbi.nlm.nih.gov/pubmed/23945937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt719 |
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