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Crystal structure of RlmM, the 2′O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA

RlmM (YgdE) catalyzes the S-adenosyl methionine (AdoMet)-dependent 2′O methylation of C2498 in 23S ribosomal RNA (rRNA) of Escherichia coli. Previous experiments have shown that RlmM is active on 23S rRNA from an RlmM knockout strain but not on mature 50S subunits from the same strain. Here, we demo...

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Detalles Bibliográficos
Main Authors: Punekar, Avinash S., Shepherd, Tyson R., Liljeruhm, Josefine, Forster, Anthony C., Selmer, Maria
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488215/
https://ncbi.nlm.nih.gov/pubmed/22923526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks727
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