Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches

The Huntington's disease gene (HTT) CAG repeat mutation undergoes somatic expansion that correlates with pathogenesis. Modifiers of somatic expansion may therefore provide routes for therapies targeting the underlying mutation, an approach that is likely applicable to other trinucleotide repeat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pinto, Ricardo Mouro, Dragileva, Ella, Kirby, Andrew, Lloret, Alejandro, Lopez, Edith, St. Claire, Jason, Panigrahi, Gagan B., Hou, Caixia, Holloway, Kim, Gillis, Tammy, Guide, Jolene R., Cohen, Paula E., Li, Guo-Min, Pearson, Christopher E., Daly, Mark J., Wheeler, Vanessa C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814320/
https://ncbi.nlm.nih.gov/pubmed/24204323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003930
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia