Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

It is common practice in genome-wide association studies (GWAS) to focus on the relationship between disease risk and genetic variants one marker at a time. When relevant genes are identified it is often possible to implicate biological intermediates and pathways likely to be involved in disease aet...

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Detalhes bibliográficos
Main Authors: Evans, David M., Brion, Marie Jo A., Paternoster, Lavinia, Kemp, John P., McMahon, George, Munafò, Marcus, Whitfield, John B., Medland, Sarah E., Montgomery, Grant W., Timpson, Nicholas J., St. Pourcain, Beate, Lawlor, Debbie A., Martin, Nicholas G., Dehghan, Abbas, Hirschhorn, Joel, Davey Smith, George
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814299/
https://ncbi.nlm.nih.gov/pubmed/24204319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003919
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