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Assumption-free estimation of the genetic contribution to refractive error across childhood

PURPOSE: Studies in relatives have generally yielded high heritability estimates for refractive error: twins 75–90%, families 15–70%. However, because related individuals often share a common environment, these estimates are inflated (via misallocation of unique/common environment variance). We calc...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Guggenheim, Jeremy A., St Pourcain, Beate, McMahon, George, Timpson, Nicholas J., Evans, David M., Williams, Cathy
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445077/
https://ncbi.nlm.nih.gov/pubmed/26019481
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