Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

It is common practice in genome-wide association studies (GWAS) to focus on the relationship between disease risk and genetic variants one marker at a time. When relevant genes are identified it is often possible to implicate biological intermediates and pathways likely to be involved in disease aet...

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Main Authors: Evans, David M., Brion, Marie Jo A., Paternoster, Lavinia, Kemp, John P., McMahon, George, Munafò, Marcus, Whitfield, John B., Medland, Sarah E., Montgomery, Grant W., Timpson, Nicholas J., St. Pourcain, Beate, Lawlor, Debbie A., Martin, Nicholas G., Dehghan, Abbas, Hirschhorn, Joel, Davey Smith, George
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814299/
https://ncbi.nlm.nih.gov/pubmed/24204319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003919
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