Reduction of Hippocampal Cell Death and Proteolytic Responses in Tissue Plasminogen Activator Knockout Mice after Transient Global Cerebral Ischemia

Knockout mice deficient in tissue plasminogen activator (tPA) are protected against hippocampal excitotoxicity. But it is unknown whether similar neuroprotection occurs after transient global cerebral ischemia, which is known to selectively affect the hippocampus. In this study, we tested the hypoth...

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Detalhes bibliográficos
Main Authors: Lee, Seong-Ryong, Lok, Josephine, Rosell, Anna, Kim, Hahn-Young, Murata, Yoshihiro, Atochin, Dmitriy, Huang, Paul L., Wang, Xiaoying, Ayata, Cenk, Moskowitz, Michael A., Lo, Eng H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814181/
https://ncbi.nlm.nih.gov/pubmed/17936515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.06.029
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