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Extension of the Thrombolytic Time Window With Minocycline in Experimental Stroke

BACKGROUND AND PURPOSE: Thrombolysis with tPA is the only FDA-approved therapy for acute ischemic stroke. But its widespread application remains limited by narrow treatment time windows and the related risks of cerebral hemorrhage. In this study, we ask whether minocycline can prevent tPA-associated...

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Main Authors: Murata, Yoshihiro, Rosell, Anna, Scannevin, Robert H., Rhodes, Kenneth J., Wang, Xiaoying, Lo, Eng H.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705574/
https://ncbi.nlm.nih.gov/pubmed/18927459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.514026
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